Expert Insights: Is there a cure for tinnitus?

[MUSIC PLAYING] Tinnitus is the perception
of phantom sound when there's no sound
in the environment. It could be ringing. It could be tonal,
1 pitch, or it could be broadband
like noise, or it could be rolling, hissing. It can vary from day to day. And even the intensity can vary. And there are
secondary symptoms. Sometimes it's associated
with anxiety and depression. You don't really need diagnosis
because if you have it, you'll know it. But if you suddenly
develop tinnitus, you should see a
doctor to rule out certain possibilities for
example brain tumors, stroke, micro stroke, or
vascular disorders.

There's not a FDA approved
effective treatment yet. But we don't have to
lose hope because there are many ways we can manage
the impact of tinnitus. And there are also many
ways people are trying, many experimental methods
to treat tinnitus, to eliminate tinnitus. People have known
for a long time that hearing loss, which
is the biggest risk factor for tinnitus
is associated with neuroinflammation in
the brain auditory pathway. And many of the risk
factors are also associated with
neuroinflammation. So these things prompted
us to hypothesize that neuroinflammation might
be the common pathway for all the risk factors to influence
the likelihood of tinnitus. Now there is a
clinical trial going on testing pro-inflammatory
cytokine blockers for treatment of tinnitus. We see a gap between
neuroinflammation and the perception
of phantom sound, we want to know what
happens in between.

So the mechanisms from
neuroinflammation to tinnitus. And we hope that
studying these mechanisms will give us a better target
for treatment of tinnitus. [MUSIC PLAYING] .

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