A New CURE For Tinnitus? | OTO-313

in this video I'm talking about a new pharmaceutical drug intended to treat tinnitus called odo 3:13 coming up hi guys cliff Olson doctor of Audiology and founder of applied hearing solutions in Phoenix Arizona and on this channel I cover a bunch of hearing related information that help make you a better informed consumer so if you're into that make sure you hit that subscribe button and don't forget to click the bell to receive a notification every time I post a new video perhaps the only thing that people are more excited about then a cure for hearing loss is a cure for tinnitus in fact I get nearly the same amount of inquiries about tinnitus treatment options as I do for hearing loss treatment options and while some of the most effective tinnitus treatments continue to be the use of hearing aids tinnitus retraining therapy otherwise known as TR T or a cognitive behavioral therapy otherwise known as CBT people still want to have that pharmaceutical drug that just gets rid of tinnitus once and for all well back in 2009 a study was conducted on a drug called gay cycling which is a non-competitive NMDA receptor antagonist which has been shown to suppress salicylate induced tinnitus in guinea pigs salicylate induced tinnitus is a type of tinnitus that is brought upon by the overuse of salicylate drugs such as aspirin k cycling is closely related to another drug that you may be more familiar with called phencyclidine which is also known as pcp which is a psychoactive drug used to elicit hallucinations nevertheless to my knowledge ski cycling does not have hallucination properties and in this particular study six individuals with signal sighted deafness and tinnitus were administered a continuous perfusion of day cycling to see if it had an impact on their overall tinnitus perception the drug solution was administered through a catheter that was implanted through the eardrum and ending at the round window allowing the gay cycling team to permeate the round window membrane for a period of forty to sixty three hours continuously at the completion of the treatment four out of six of these participants experienced temporary relief of their tinnitus symptoms and while this may not seem like a big deal it was enough for a company named autonomy to take this gay cycling through a phase 1 and phase 2 FDA clinical trial to see if it is safe and if it's effective to treat tinnitus however there are two big differences between these clinical trials and this study that was completed in 2009 first is the double-blind nature of these clinical trials on top of there being more participants in the clinical trials as well half of these individuals will be receiving a placebo and the other half will actually be receiving the gay cycling in the original study all six individuals used a cycling so it is unclear whether or not this was just a placebo effect or whether or not gay cycling actually worked the second difference is the delivery method of the gay cycling drug back in 2009 the participants received a continuous perfusion of gay cycling that was making contact with the round window for forty to sixty three hours well in the clinical trials they're only doing an intro tympanic injection to get the gay cycling into the middle ear space to make contact with the round window so I don't know how much more effective that could possibly be than to have a continuous stream of gay cycling for forty to sixty three hours but it makes me question whether or not the dosage is going to be high enough to actually evoke a positive response with any luck this single injection will prove to be a safe delivery method and hopefully it ends up resulting in a reduction an overall tinnitus perception these clinical trials are expected to be completed in May of 2020 and we should see some published data hopefully by the end of the year now I will go ahead and link the website clinical trials gov for the Auto 313 clinical trial so you can check it out yourself in the meantime I'm gonna keep my eye on this company autonomy who's also creating other pharmaceutical drugs to treat conditions like hearing loss and Meniere's disease so I like where this company is going they have a really direct focus on treating ear related conditions and so hopefully I'll be able to keep you posted on some updates with these other drugs as well currently there is no cure for tinnitus but there is help if you want to continue your research check out the American tinnitus Association website that I will link in the description of this video and if you want some help right now what you need to do is you need to find an odd geologist who specializes in tinnitus treatment they can get your questions answered and they can get you set up with a treatment option that can actually reduce your perception of tinnitus so the help is out there you just have to go find it that's it for this video if you have any questions leave them in the comment section below if you like the video please share it if once the other video is just like this one go ahead and hit that subscribe button also feel free to check out my website dr.

cliff AUD calm [Music].

You May Also Like